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The Cardinals arrive in Anaheim having dropped four straight, a skid that has turned what looked like a promising second half into a scramble to stay relevant. St. Louis is two games below .500 in its last ten and needs to find answers fast. The Angels, meanwhile, have won three in a row and are playing with something resembling momentum — a rare commodity in a season that has largely gone sideways for Anaheim.

Jordan Walker is the Cardinals’ most dangerous weapon right now, hitting .292 with 22 home runs and 76 RBI, numbers that put him among the more productive outfielders in the National League. On the other side, Zach Neto has been a consistent force for the Angels, with 19 home runs, 69 runs scored, and 13 stolen bases — a well-rounded threat who can hurt a team in multiple ways.

The Angels’ bullpen situation adds another layer of intrigue. All-Star closer Riley O’Brien — now listed in the Cardinals’ player data with 25 saves — imploded in the most recent meeting between these clubs, retiring just one batter in the ninth before the Angels rallied to win. That collapse, and how both teams’ late-inning arms respond going forward, could define this matchup.

St. Louis Cardinals at Los Angeles Angels Game Information

Game Date: July 22, 2026
Game Time: 04:07 PM ET
TV Channel: Angels Broadcast Television – ABTV2LV, St. Louis Cardinals, and MLB.TV – Los Angeles Angels
Location: Angel Stadium, Anaheim, CA
Live Stream: Fubo (free trial)

Game Preview

St. Louis sits 11.5 games back and cannot afford to let a struggling opponent extend the losing streak to five. The Cardinals are 4-6 over their last ten games, and the math gets harder with every loss. For the Angels, at 41-61 and 10.5 games back, the standings are less the point than the winning habit itself — three straight victories represent the kind of run that can reshape a clubhouse’s sense of what’s possible in the second half. A fourth consecutive win would be their longest streak in some time.

Los Angeles Angels Team Statistics and Rankings

Win-Loss Record: 41-61
Home Record: 24-27
Away Record: 17-34
Division Record: 6-15
Streak: 3 Win streak
Winning Percentage: .402

St. Louis Cardinals Team Statistics and Rankings

Win-Loss Record: 51-49
Home Record: 26-26
Away Record: 25-23
Division Record: 15-13
Streak: 4 Loss streak
Winning Percentage: .510

Stat Leaders

Los Angeles Angels (41-61, #5 in division)

Batting Average Leader: Omar Martinez, 0.333
RBI Leader: Jo Adell, 57 RBI
Home Run Leader: Zach Neto, 19 HR
Runs Leader: Zach Neto, 69 Runs
Hits Leader: Jo Adell, 95 Hits
Stolen Bases Leader: Zach Neto, 13 SB
ERA Leader: Samy Natera Jr., 2.60 ERA
Strikeout Leader: Reid Detmers, 130 K
Wins Leader: José Soriano, 8 W
Saves Leader: Jordan Romano, 4 SV

St. Louis Cardinals (51-49, #4 in division)

Batting Average Leader: Jordan Walker, 0.292
RBI Leader: Jordan Walker, 76 RBI
Home Run Leader: Jordan Walker, 22 HR
Runs Leader: Jordan Walker, 64 Runs
Hits Leader: Jordan Walker, 110 Hits
Stolen Bases Leader: Jordan Walker, 14 SB
ERA Leader: Ryan Fernandez, 2.70 ERA
Strikeout Leader: Matthew Liberatore, 95 K
Wins Leader: Andre Pallante, 10 W
Saves Leader: Riley O’Brien, 25 SV

What to Watch For

Walker is the Cardinals’ clearest must-watch presence. His 110 hits, 22 home runs, and 76 RBI represent the kind of production St. Louis desperately needs to lean on during a four-game skid. Alec Burleson has been nearly as reliable, batting .282 with 15 home runs and 69 RBI, giving the Cardinals a legitimate middle-of-the-order punch even when the team around them has struggled to close out games.

For the Angels, Nolan Schanuel has been quietly steady at .284 with 86 hits and 35 RBI, while Wade Meckler is hitting .302 and provides a different kind of threat at the top of the lineup. Jo Adell’s 57 RBI make him one of the more productive run-producers in the Angels’ order.

On the mound, Michael McGreevy carries a 2.92 ERA and four wins for St. Louis, making him one of the more reliable arms in their rotation. The Angels’ Walbert Ureña has been effective as well, posting a 2.78 ERA with 83 strikeouts and six wins. If either pitcher can go deep into the game and keep the bullpen out of it, that alone could determine which team’s current trajectory continues.

Los Angeles Angels Injury Report

Sebastián Rivero – Hand (D10) – The Los Angeles Angels placed C Sebastián Rivero on the 10-day injured list due to left hamate fracture.
Travis d’Arnaud – Foot (D60) – The Los Angeles Angels transferred C Travis d’Arnaud to the 60-day injured list from the 10-day injured list with a right foot plantar fasciitis.
Yusei Kikuchi – Shoulder (D60) – The Los Angeles Angels transferred LHP Yusei Kikuchi to the 60-day injured list due to left shoulder inflammation.
Jack Kochanowicz – Elbow (D60) – The Los Angeles Angels transferred RHP Jack Kochanowicz from the 15-day injured list to the 60-day injured list due to surgery.
Anthony Rendon – Hip (D60) – The Los Angeles Angels placed INF Anthony Rendon on the 60-day injured list.
Ben Joyce – Shoulder (D60) – The Los Angeles Angels transferred RHP Ben Joyce to the 60-day injured list as he recovers from his right shoulder surgery.
Yoán Moncada – Knee (D60) – The Los Angeles Angels transferred INF Yoán Moncada to the 60-day injured list with right knee inflammation.
Adam Frazier – Elbow (D10) – The Los Angeles Angels placed INF Adam Frazier on the 10-day injured list with right elbow inflammation.
Robert Stephenson – Elbow (D60) – The Los Angeles Angels placed RHP Robert Stephenson on the 60-day injured list due to a ligament and flexor repair surgery on his right elbow.

St. Louis Cardinals Injury Report

Ramón Urías – Elbow (D60) – The St. Louis Cardinals transferred INF Ramón Urías to the 60-day injured list due to right elbow lateral epicondylitis.
JoJo Romero – Appendix (D15) – The St. Louis Cardinals placed LHP JoJo Romero on the 15-day injured list with appendicitis.
Max Rajcic – Elbow (D60) – The St. Louis Cardinals transferred RHP Max Rajcic from the 10-day injured list to the 60-day injured list with a right elbow soreness.

Los Angeles Angels Upcoming 2026 Schedule

July 22, 2026 vs St. Louis Cardinals
July 24, 2026 at San Francisco Giants
July 25, 2026 at San Francisco Giants
July 26, 2026 at San Francisco Giants
July 27, 2026 vs Houston Astros
July 28, 2026 vs Houston Astros
July 29, 2026 vs Houston Astros
July 31, 2026 vs Milwaukee Brewers
August 01, 2026 vs Milwaukee Brewers
August 02, 2026 vs Milwaukee Brewers

St. Louis Cardinals Upcoming 2026 Schedule

July 22, 2026 at Los Angeles Angels
July 23, 2026 vs Arizona Diamondbacks
July 24, 2026 vs Cincinnati Reds
July 25, 2026 vs Cincinnati Reds
July 26, 2026 vs Cincinnati Reds
July 27, 2026 vs Chicago Cubs
July 28, 2026 vs Chicago Cubs
July 29, 2026 vs Chicago Cubs
July 30, 2026 vs Chicago Cubs
July 31, 2026 at Toronto Blue Jays

Our game previews are produced programmatically using real-time data via Sportradar and AI writing tools. Articles are regularly reviewed for accuracy before publication.